As I stated previously I started replaying skyrim. In hopes it will be the last time. I'm guessing probably not. I just finished up a delve into a dwemer ruin, and was struck by the fact that the puzzle within could also be a equally cool D&D puzzle.
Here is some information on the tonal resonator puzzle in the game. http://elderscrolls.wikia.com/wiki/Tonal_Resonator
Below is a spoiler alert video on how to do it in game.
And here are my thoughts on a D&D puzzle. Rather than use 5 different tonal resonators (which might become difficult for players) I would suggest using three. A clue, like in the game could be left by a dead npc to the correct first position.
Correct Sequence: The resonators need to be pushed in the following order.
2, 3, 1
The resonators can be labelled the following:
In the case of 3 being pushed first, geysers of flames will blast the players 2d6 damage.
In the case of 1 being pushed first, a pit trap will open dropping the players down 10 feet (1d6 damage)
In the case of the second number being incorrect, a group of 1d4 automatons will burst out of the walls and attack: AC 9 (10) HD 2 ATT 1d6+2
As an alternative, you could use face cards from a card deck and have the players attempt to put them in the correct order.